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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKB2
All Species:
6.67
Human Site:
S22
Identified Species:
16.3
UniProt:
Q00653
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00653
NP_001070961.1
900
96749
S22
Y
D
D
F
K
L
N
S
S
I
V
E
P
K
E
Chimpanzee
Pan troglodytes
XP_001168576
837
90846
K17
I
L
H
V
T
K
K
K
V
F
E
T
L
E
A
Rhesus Macaque
Macaca mulatta
XP_001104566
876
94023
S22
Y
D
D
F
K
L
N
S
S
I
M
E
P
K
E
Dog
Lupus familis
XP_850995
899
96492
P22
Y
D
D
F
K
F
D
P
C
I
A
E
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK5
899
96814
P22
Y
D
D
F
E
F
S
P
S
I
V
E
P
K
D
Rat
Rattus norvegicus
NP_001008350
898
96721
P22
Y
D
D
F
E
F
S
P
S
I
V
E
P
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98150
906
99648
H22
D
D
F
S
F
G
S
H
M
V
E
Q
K
E
P
Frog
Xenopus laevis
O73630
958
105836
T28
R
N
G
M
G
Y
S
T
A
L
L
N
P
I
V
Zebra Danio
Brachydanio rerio
NP_001001840
902
98760
A37
D
L
P
Y
M
P
E
A
F
E
V
K
H
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999819
1125
124026
L44
N
D
F
D
S
N
D
L
M
H
L
P
V
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
95.1
92.5
N.A.
91.7
90.8
N.A.
N.A.
66.8
50.9
49.6
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
55
96
95.1
N.A.
94.8
94.1
N.A.
N.A.
76.7
65.9
65.1
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
0
93.3
66.6
N.A.
66.6
66.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
33.3
46.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
20
70
50
10
0
0
20
0
0
0
0
0
0
0
20
% D
% Glu:
0
0
0
0
20
0
10
0
0
10
20
50
0
30
30
% E
% Phe:
0
0
20
50
10
30
0
0
10
10
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
10
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
50
0
0
0
10
0
% I
% Lys:
0
0
0
0
30
10
10
10
0
0
0
10
10
50
10
% K
% Leu:
0
20
0
0
0
20
0
10
0
10
20
0
10
0
0
% L
% Met:
0
0
0
10
10
0
0
0
20
0
10
0
0
10
0
% M
% Asn:
10
10
0
0
0
10
20
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
30
0
0
0
10
60
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
0
40
20
40
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
10
40
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _